Search on: SMAD PROTEINS, INHIBITORY 
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Descriptor English:   Smad Proteins, Inhibitory 
Descriptor Spanish:   Proteínas Smad Inhibidoras 
Descriptor Portuguese:   Proteínas Smad Inibidoras 
Synonyms English:   I-Smad Proteins
Inhibitory Smad Proteins  
Tree Number:   D12.644.360.024.334.200
D12.776.157.057.170.249
D12.776.476.024.428.249
Definition English:   A sub-family of smad proteins that inhibit cell signaling by RECEPTOR-REGULATED SMAD PROTEINS. They form autoinhibitory feedback loops in the TGF-BETA signaling pathway and mediate signaling cross-talk with other signaling pathways 
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50785 
Unique Identifier:   D051897 

Occurrence in VHL:
 

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